Optimizing cardiovascular health is a leading concern for many adults, and maintaining balanced cholesterol levels are an important part of that process. Though cholesterol can be consumed through food, circulating cholesterol levels are primarily produced and controlled by the liver using the rate control enzyme, HMG-CoA reductase (HMGCR). Because of its pronounced role in cholesterol synthesis, inhibiting HMGCR has become a primary target of many traditional therapies.
Numerous clinical trials have shown the specific BPF found in Bergamot BPF works at the level of the liver to help maintain and support healthy cholesterol levels and preserve coronary arteries by maintaining normal inflammatory balance.
What are Bergamot Polyphenolic Fractions?
Bergamot (Citrus bergamia) is a citrus plant that grows almost exclusively in the narrow coastal Calabria region in southern Italy. The local population quickly discovered bergamot juice could be used to help support healthy cholesterol levels and optimize cardiovascular wellness.
Bergamot’s health benefits derive from its unique profile of phenolic compounds such as, neoeriocitrin, neohesperidin, naringin, rutin, neodesmin, rhoifolin and poncirin. Naringin has been shown to be beneficial in maintaining normal inflammatory balance, while neoeriocitrin and rutin have been found to exhibit a strong capacity to quench free radicals and maintain healthy LDL cholesterol levels. Also, bergamot is rich in brutieridine and melitidine, which have a unique ability to dampen HMG-CoA reductase.
Using a patented extraction technology through collaborative works of various universities and research institutions, Bergamot BPF contains Bergamonte®, BPF/Bergamot Polyphenolic Fraction (by H&AD), the highest concentration available of these potent phenolic compounds. Clinical trials quoted were conducted on BPF.