How to Apply Women's Hormonal Creams

It is normal for women to experience a decline in hormones with aging; Hormone Replacement Therapy (HRT) is used in an attempt to get these hormone levels back to a normal level. HRT cream is a dosage form that includes hormones, typically progesterone and estrogen, in a cream formulation for absorption through the skin. 

How to Apply HRT Cream

Step 1: Wash hands with soap and water.

How to wash hands

Step 2: Measure the prescribed amount of cream from the syringe and rub completely into clean, dry, skin on the inside of the wrist, inside the upper arm, the inner thigh, or lower abdominal area.

**Unless otherwise instructed by your physician or pharmacist

Step 3: Wash hands thoroughly with soap and water immediately after applying. 

Talk to your doctor or pharmacist

Using HRT should be painless and easy. Talk with your doctor or pharmacist if you have any questions or are having trouble using the cream properly. Discontinue use and check with your doctor or pharmacist if you notice any redness, itching, swelling, or other side effects not present before you started using this medicine.

Woman with a question

Question: What should I do if I miss a dose?
Answer: If you miss a dose of your HRT cream applies the missed dose as soon as possible. If your next dose is less than 4 hours away, then skip the missed dose and simply apply the next dose at the time that corresponds to the dosing regimen on your prescription label.

Question: What if my child or pet is exposed to my HRT cream?
Answer: If a child comes into direct contact with the areas where the HRT cream was applied, wash the child’s skin with soap and water as soon as possible. Contact the child’s healthcare professional if you notice any nipple swelling or breast development in girls or breast enlargement in boys and that the child may have been exposed to an HRT topical cream. 

Question: What if my pet is exposed to my HRT cream?
Answer: Do not allow pets to lick or touch the arm where the HRT cream was applied. Contact your veterinarian if your pet shows signs of the nipple or vulvar enlargement and let them know that your pet may have been exposed to an HRT topical product.

Helpful Tips

1. Allow the cream time to dry, about 10-20 minutes, before covering up with clothing
   

   Tips

2. To ensure maximum absorption and effectiveness you should wait at least two hours before showering or swimming once this medication has been applied to the skin
3. Rotate application sites with each application. Do not repeatedly apply the medication to the same area
4. How to use the syringe: If you have a 10 ml syringe and the prescription is written to apply 1 ml, then you would push the plunger of a full 10 ml syringe until it reaches the 9 ml mark – indicating 1 ml has been dispensed.
5. Store this medication in a closed container, away from heat, moisture, and direct light and out of reach of small children and animals. 
6. Precautions: This hormone cream can be transferred to another person if they rub or touch the skin where the medication was applied or if they touched your unwashed hand. You should wash the area well if you plan to have skin-to-skin contact with another person and dispose of your HRT products out of the reach of children and pets.  The locations of cream application are meant to be easily covered with clothes to avoid the transfer of cream to others. Virilization (changes in biological development) has also been reported in children with secondary exposure to some topical hormone preparations. Children should not come in contact with unwashed or unclothed application sites.

We can ensure your next medication is compounded with the same quality and care as this one.
When you approach the end of your compounded cream call:
 Coast to Coast Compounding (303-237-4478)
*Please allow 24-48hr to prepare your cream*