Ortho Spore IG™ is a spore-based, broad-spectrum probiotic formula designed to promote a healthy gut microflora, protect mucosal integrity, and relieve small intestinal bacterial overgrowth (SIBO). Uniquely included in this formula are serum-derived bovine immunoglobulins that bind to and eliminate microbes and toxins that are common in SIBO.
- Bacillus coagulans: Bacillus coagulans has been shown to increase the commensal GI microbiota. B. coagulans also significantly improved bowel movements in healthy adults with occasional constipation, as well as decreased abdominal discomfort.
- Bacillus clausii: B. clausii is commonly used as a probiotic to promote balance in the microbiome and has showed promising results in individuals with SIBO.
- Bacillus subtilis: Bacillus subtilis has been shown to relieve GI distress in patients.
- Serum-derived bovine immunoglobulins: Broad-spectrum binding capabilities demonstrate the positive influence of serum-derived bovine immunoglobulins. This binding and elimination decreases microbe and toxin encounters by the immune system and resets immune tolerance.
Probiotics are live organisms and must be shelf stable through the expiration date, so they can be precisely delivered to the intestinal tract to have maximum benefit. Bacillus spores can transition between a dormant and an active form, depending on the environment. Bacillus spores remain dormant in harsh environments until they reach more favorable environments like the human gastrointestinal tract. In its dormant spore form,
Bacillus surrounds itself with an endospore, which is a tough, natural outer shell that protects it from light, heat, pressure, acid, lack of oxygen, and other environmental factors. Bacillus
changes into its active form in the large intestine to colonize the gut to encourage microbial diversity of commensal gut bacteria. In its active form, Bacillus can increase microbial diversity by changing the pH, and increasing the production of short-chain fatty acids. The combination of specific strains, particularly Bacillus coagulans, Bacillus clausii, and Bacillus
subtilis, relieve symptoms for common GI complaints and reinforce healthy gut function.3 The discovery that the gut barrier plays a key role in immune health fueled the search to strengthen it. Research has shown
that the binding capabilities of immunoglobulins have a positive effect on gut barrier function.4 In the search for innovative ways to improve microbiome diversity, we have
combined our blend of spore-forming probiotics alongside immunoglobulins uniquely shown to bind to bacteria and toxins, driving immune response. IgG helps to maintain a healthy intestinal immune system by binding a broad range of microbes and toxins within the gut lumen. As these unwanted triggers are removed, it resets healthy immune tolerance and
† These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease. builds a stronger barrier to the external environment in the gut. Serum-derived bovine immunoglobulins have the highest IgG concentration available for GI and immune challenges where allergens are a significant concern.