Vaginal suppositories are a dosage form that contains medication intended to be inserted into the vagina to deliver the medication directly to that area. They can come in different shapes or sizes with the most common having a narrow end at one side. The suppository typically melts once placed inside the body where the medication is then absorbed. Medications placed into a vaginal suppository may include hormones, anti-infectives, or medications to treat vaginal dryness, atrophy, or pain. Talk with your doctor or pharmacist to see if compounded vaginal suppositories are the right choice for you.